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Archive for the ‘ gynecology ’ Category

Birth Control Study

Tuesday, October 13th, 2015

Today, women have a variety of contraception options when it comes to family planning.  Currently, CCRstudies is testing an investigational vaginal ring for birth control.  For some women, the birth control ring provides an option for those who are not interested in taking a daily oral medication for birth control, or for those who do not want the more long term option of an IUD. Eligible research volunteers ages 18 and above will receive the study birth control medication at no cost and will be reimbursed for their time and travel.

During the vaginal ring study, study patients health will be monitored throughout the course of the clinical trial. Study volunteers will also receive study-related breast, gynecological, and cervical exams at no cost.

Those women who are interested in learning more about the currently enrolling birth control study can contact a member of the CCRstudies team at 860-443-4567. Study doctors include Robert M. Spitz, MD and Craig E. McKnight, MD, PhD.

Do You Pee When You Laugh?

Tuesday, September 15th, 2015

Do you pee when you laugh, cough, sneeze or exercise?  It can be embarrassing and annoying!  Some women tacitly except this condition and chalk it up to once having had big babies or getting older.  Leaking pee when you laugh, cough, sneeze or exercise is called Stress Urinary Incontinence. This is a real medical condition.  Clinical research is currently underway in New London to test a discreet, disposable investigational product that may prevent small bladder leaks that occur when women laugh, cough, sneeze or exercise.

Some women find themselves wearing panty liners or pads 24/7, avoiding activities such as Zumba, and urging people not to make them laugh to avoid urine leaks.  Take a listen to the radio spot below to learn more, or call 860-443-4567.


Stress Urinary Incontinence

Tuesday, July 21st, 2015

Stress Incontinence Postcard

The following article originally appeared in our “Health Wise” column in the local TIMES newspaper:

The warmer summer weather brings with it a chance to get out and get active. For some people, this may mean biking, running, hiking, gardening or any number of outdoor activities that can be enjoyed in our beautiful shoreline communities. For some women, however, increased activity might just mean the increase in a rather unpleasant and seldom addressed problem – urine leakage.

Stress Urinary Incontinence is the medical term for the involuntary loss of urine that occurs in some women when they laugh, cough, sneeze, or exercise. For many women, this is a daily problem that often gets ignored or tacitly accepted. Stress Urinary Incontinence, or in more simple terms, leaking pee, is the result of stress placed upon the bladder caused by activity. Weaker pelvic and sphincter muscles adding to the sudden pressure placed upon the bladder can lead to leakage. The unspoken acceptance of this condition might result from the thought pattern some women have of simply “dealing with it,” for lack of a better term. “I had big babies,” “I’m getting older,” or “I’ve been leaking for years,” may be some of the reasons women find themselves quietly accepting this condition and not reporting their symptoms to a health care provider.

Today, the term “stress” is often associated with emotional burdens. In regards to the condition of Stress Urinary Incontinence, this particular stress is purely physical. Emotional issues, financial burdens, and other problems people associate with the stressors faced today likely won’t cause a woman to leak urine.

Susie of Waterford recently recounted a story in which she ended up leaking urine while running to catch a connecting flight in a busy airport. The strain placed upon her bladder while dashing to catch her flight made for a pretty uncomfortable journey home! While Susie wasn’t running a marathon, female athletes, who are in great physical condition, can also experience stress urinary incontinence during physical activity.

Past treatments for Stress Urinary Incontinence have included medication, behavioral therapy, and pelvic floor exercises, which most of us can agree rarely get done. Here in New London, there is a clinical trial underway to test an investigational device designed to stop urine leaks. The disposable device is not a medication and can be inserted and removed by the user. The clinical study is being conducted at 342 Montauk Avenue in New London by Timothy Barczak, MD. Those interested in the trial can learn more by calling 860-443-3700.

The community educators at CCRstudies in New London are available to visit your community group to share further information about Stress Urinary Incontinence. Call 860-443-4567 to start the discussion!

MOMS Night Recap

Thursday, June 25th, 2015



Thank you to all of the wonderful MOMS Club members and friends who joined us recently for an evening of painting fun at the Drunken Palette in New London, CT.  Our event served to share information about HSDD, Hypoactive Sexual Desire Disorder,  and to discuss the Reconnect Study.  We had a lot of laughs, some great gift card giveaways, and fellowship among friends!  We are looking forward to more community events and outreach. Felicia Stevens, proprietor of the art studio, deserves special thanks for keeping the evening lively!

If your community group of organization is interested in learning more about clinical trials, please contact MaryLou Gannotti at CCRstudies at 860-443-4567, or e-mail

MOMS Night Out

Wednesday, May 27th, 2015


Fun is in the air as we look forward to CCRstudies inaugural MOMS Night Out at the Drunken Palette in New London.  We’re hosting members of the New London MOMS Club for an evening of painting and lively conversation.  We’ll be highlighting the RECONNECT study for decreased sexual desire in women.  The MOMS Night Out takes place on Wednesday, June 24th at 6:30 p.m.  We are  looking forward to connecting with local moms, discussing the RECONNECT study, and sharing information regarding clinical trials, all while painting a lovely scene of our local Ocean Beach Park.

Female Sexual Function and Dysfunction

Tuesday, May 19th, 2015


When most of us think of sex, we conjure up images of romance, love, and possibly lust. But what happens if a woman’s interest in sex fades, if sexual thoughts and fantasies are just a memory?  What should be done when a woman’s desire to be sexual has left and she no longer feels responsive to her partner’s advances? This all depends on how the change affects the woman in question. One woman may consider it a natural and normal life progression, while for another the loss becomes a source of personal distress.

For the research scientist, talk of romance and love and lust is translated into “the sexual response cycle” – desire, arousal, plateau, orgasm and resolution. It sounds so clinical, but it serves a purpose in research as different approaches may be necessary for problems that arise in each phase of that cycle. Research is being conducted to find solutions for those women who develop distress when experiencing the common changes described above. Currently we are focused on the desire phase of the cycle, from which arousal and orgasm will hopefully flow.

Hypoactive Sexual Desire Disorder (HSDD) is defined as “the persistent or recurrent deficiency (or absence) of sexual fantasies/thoughts, and/or desire for or receptivity to sexual activity, which causes personal distress.” We are currently conducting a clinical trial of an investigational medication for treatment of HSDD. As with most research into treatment of this problem, we are focused on women who previously had what they felt was a satisfying level of interest in sex, but who have become distressed with experiencing a decrease in interest. Women who have always had a low level of interest in sex are thought to be less likely to benefit from the medications currently being studied

Call 860-443-4567 to learn more about our current clinical trial for HSDD or e-mail to learn more.

The study is being conducted by Robert M. Spitz, MD, Craig E. McKnight, MD, PhD, and Merrilyn McNatt, APRN.



Welcome Dr. McKnight!

Monday, May 18th, 2015
Melissa Gomez and Craig E. McKnight, MD, PhD

Melissa Gomez and Craig E. McKnight, MD, PhD

CCRstudies welcomes Craig E. McKnight, MD, PhD, and Melissa Gomez, a member of his nursing staff,to our study team.

Dr. McKnight currently serves as the Medical Director at Craig E. McKnight, MD, PhD, LLC, a private gynecology practice in New London located on Montauk Avenue.

Dr. McKnight’s areas of interest include gynecology, urinary incontinence and infertility. He has worked as an OB-GYN in private practice, has been involved in research, and has served as a member of the teaching faculty at Yale New Haven Hospital. Dr. McKnight holds a BS in Zoology from Iowa State University, an MA in Zoology from the University of South Florida, a PhD from the University of Pennsylvania and an MD from Jefferson Medical College.  Dr. McKnight will be working as a Sub-Investigator on some of the clinical research trials at CCRstudies, including the Birth Control study, Decreased Sexual Desire in Women, and Overactive Bladder.

Melissa Gomez, a member of the nursing staff at Craig E. McKnight, MD, PhD, LLC in New London, will be working as a Research Assistant on a variety of trials at CCRstudies. With a focus and training in nursing,  Melissa worked as a Certified Nurse’s Aide for many years, and is a graduate of Norwich Free Academy. Melissa earned a diploma in nursing from Stone Academy in East Hartford and has been trained as an LPN.  Melissa has been working in the medical field for the past several years, and has experience in residential care. Her friendly demeanor and attention to detail will serve her well in the role she plays in the clinical trial process.

We are delighted to welcome Dr. McKnight and Ms. Gomez to the professional team at CCRstudies!

Drip, Drop…..

Tuesday, May 12th, 2015

Empire was one of the hottest shows on Fox TV this past season.  Intrigue, drama, romance, treachery and who could forget the infamous rap “drip, drop, drip, drippity, drop?”  Here at CCRstudies however, the rap takes on a whole new meaning!

Have you ever heard of the term “stress urinary incontinence?”  Many people have not, BUT, many of those same people live with the condition.  Stress Urinary Incontinence is the unintentional loss of urine. In other words – LEAKAGE!  For some women, this loss of urine occurs when they pee, cough, laugh or sneeze.  By putting stress on the bladder, these activities result in the loss of urine.  Those who live with the condition often think there’s nothing they can do about it and live with the daily distress of leakage.  Currently, however, a clinical trial is underway in New London to test an investigational device to be used by women for the prevention of urine leaks that occur with exercise and other activities. This is a disposable product that will be used daily during the assessment period of the study.

There is no cost to participate in the research study.  Participants will receive reimbursement for time and travel.  To help test this product, or for more information call 860-443-3700.  Study conducted by Dr. Timothy Barczak.

Nightingale Awards

Tuesday, May 5th, 2015


Congratulations to Merrilyn McNatt, APRN.  She will be presented with a Nightingale Award for Excellence in Nursing on Thursday, May 7th, 2015 at the Mashantucket Pequot Museum and Research Center.  She is among 50 nurses who will be recognized for excellence in their profession by the VNA of Southeastern Connecticut, who organize the event.

Merrilyn has worked as a Sub Investigator on a variety of clinical trials at CCRstudies. Ms. McNatt has a BSN from the Medical College of Georgia, a Master’s degree in Maternal/Child  Nursing from the University of Connecticut with  post-graduate work completed at the University of Rhode Island in the area of family practice.

Best wishes to Merrilyn on being recognized for her outstanding contributions to the nursing profession!



Birth Control Study

Monday, April 27th, 2015

Today, women in the United States have a vast array of birth control choices.  Many birth control options are heavily advertised on television and in magazines, with sleek ads of lovely, long legged women out for a night on the town.  This wasn’t always the case in the United States! Just 50 years ago, in 1965, unmarried women in 26 states did not have legal access to birth control.  That same year, the Supreme Court ruled in Griswold versus Connecticut that it was “unconstitutional for the government to prohibit married couples from using birth control.”  As the saying goes, “we’ve come a long way, baby!”

Women who are ages 18-35 might be interested in learning more about a currently recruiting trial for birth control being conducted at CCRstudies in New London.  This year long study is testing the safety and contraceptive efficacy of an Intravaginal Ring with LNG (Levonorgestrel) over one year.  No insurance is needed to participate, and there is no cost for study-related medication and exams. Reimbursement available for time and travel.

Study will be conducted by Robert M. Spitz MD, Craig E. McKnight MD, PhD, and Merrilyn McNatt APRN.

Call 860-44-4567 to learn more about CCRstudies current birth control study.