Conducting clinical research studies with
Call to participate

Archive for the ‘ Overactive Bladder ’ Category

Does Frequent Urination Impact Your Summer?

Monday, July 9th, 2018

Summer’s here.  So many things to do – beaching, boating, hanging out at picnics.  The only problem is, you pee all the time and avoid these activities.  If you can’t be near a bathroom, you can’t go.

Many women live with the symptoms of Overactive Bladder also known as OAB but are too embarrassed to discuss this issue.  The frequent and urgent need to urinate, having some leakage or wetting accidents, and getting up in the night to pee are some of the symptoms of OAB.  Sound like you?

Coastal Connecticut Research is conducting a research study evaluating an investigational medication for women who live with Overactive Bladder.  Study gynecologist is Dr. Robert Spitz.  If you are a woman who is living with the symptoms of OAB and you are interested in learning more about research, call (860) 443-4567 to speak with a member of the CCRstudies team.

Do You Pee Frequently?

Monday, May 7th, 2018

A lot of women shrug off the fact they urinate 8 or more times each day.  “I’ve had babies, my bladder is weak,”  “I’m getting older,” “coffee makes me pee,” are some of the phrases you might have heard a friend or even yourself utter.

Overactive Bladder, also known as OAB is a real medical condition.  Symptoms of OAB include a sudden and strong need to urinate right away (or, when you gotta go, you gotta go!).  People with OAB might also urinate 8 or more times each day, leak a little after having the sudden urge to urinate and wake up during the night to pee.

46 million adults in the US over the age of 40 experience these symptoms.

Coastal Connecticut Research is currently conducting an Overactive Bladder research study.  Those who wish to learn more are invited to contact a member of the CCRstudies team at (860) 443-4567.   There is no cost to participate in a clinical research study and no insurance is needed.

CCRstudies on the Air!

Tuesday, January 3rd, 2017

Make sure your digital dial is set to Wolverine Radio next week!  CCRstudies will be hitting the airwaves with Wolverine Radio’s Mike Minarsky on January 10th from 9-10am for the morning show.  We look forward to sharing information regarding clinical research with Wolverine Radio listeners.

You can tune into the station on 1690 am or stream at .  Morning show host Mike Minarsky is graciously providing us with one hour to share information regarding our enrolling and upcoming clinical research studies.  We’ll discuss conditions such as overactive bladder, memory loss, constipation, migraine headaches, and feminine dryness.  We encourage listeners to call in with their questions, or call  us directly after the show at (860)443-4567.  MaryLou Gannotti will be chatting with Mike and we are hoping Diane Palmer, RN, Site Administrator and Plainfield native, makes an appearance back in her Eastern Connecticut stomping grounds.

We’ll “see” you on the radio!

Overactive Bladder

Monday, December 19th, 2016

Susan, 67,  had lived with frequent urination for the past several years.  Rushing to the bathroom, being unable to sit through a movie, always making a trip to the restroom before ordering at a restaurant and returning to the restroom prior to dessert were par for the course for Susan.  A few times a week, Susan barely made it to the bathroom since she felt such a sudden urge to urinate.  She wore pads daily, an expense she did not like incurring but felt was necessary for those times she didn’t quite make it to the toilet and leaked.

Susan was unaware she was living with a real medication condition known as Overactive Bladder or OAB.  With a normal bladder, you control when you go to the bathroom.  With Overactive Bladder, you are controlled by the frequent and sudden urges to urinate.

In addition to not knowing she was living with Overactive Bladder (OAB), Susan was also unaware there were medications on the market to help control the symptoms of this condition.  She heard about a research study seeking women living with Overactive Bladder and it finally occurred to her this is something she might be living with.

Unfortunately, quite a few women living with OAB might dismiss their symptoms.  Some women may attribute their lack of bladder control to aging, childbirth or weakened muscles.  Some might think these symptoms are normal, or there is nothing they can do about it.

Investigational medications and FDA-approved medications continue to be tested in the clinical trial process to evaluate their safety and efficacy.  Clinical research is underway in New London on a FDA-approved medication.  Women who are 65 and older who visit the bathroom more than 8 times per day might be interested in learning more.  Robert M. Spitz, MD is the study doctor.  Call (860)443-4567 or email to learn more.

Overactive Bladder Research Study

Tuesday, July 12th, 2016

Overactive Bladder (OAB) is a condition experienced by 200 million people throughout the world. People living with OAB often experience a sudden and urgent need to use the bathroom, waking up to go to the bathroom more than once per night, incontinence, and frequent trips to the bathroom.  What causes OAB is not fully understood, but it is believed the bladder muscle becomes overactive and contracts when you don’t want it to.

Treatments for OAB are available, but different age groups respond in different ways to medication.  CCRstudies is currently conducting a clinical research trial for women 65 and older who are living with OAB.  The study medication being evaluated is FDA-approved.  There is no cost to participate in the clinical research study, and no cost for the study medication.  There are 7 office visits over the course 20 weeks.  Reimbursement of up to $525 is available to the study patient for time and travel.  Dr. Robert Spitz is the study doctor, and all visits will take place in New London at 342 Montauk Avenue.

If you are a woman over 65 who is living with Overactive Bladder, you are welcome to contact a member of the CCRstudies team to learn more about this clinical research trial. Call (860)443-4567, or email 

CCRstudies in the Community

Monday, December 7th, 2015

Donor DriveLL2

Members of the CCRstudies team have had the pleasure of meeting a variety of individuals in our region thanks to our recent community events! We thank the gracious staff of CorePlus FICU in Groton for partnering with CCRstudies to host a bone marrow donor drive. We met many who were willing to join the National Bone Marrow Donor Registry. We’ve learned Maria, 21, a college student from Groton, is in need of a bone marrow donor as she fights blood cancer. Thanks to those who attended our event to help those in need!

In addition, many thanks to Joanne Moore of Shoreline Physical Therapy in East Lyme. Joanne offered her space to accommodate guests for a “lunch and learn” event.  We discussed the signs and symptoms of Overactive Bladder, Stress Urinary Incontinence, and our currently enrolling clinical trials. We encouraged those in attendance to consider volunteering.  Many have given blood or donated their time and talent in other ways.  Why not consider being a research volunteer?

If you are interested in teaming with CCRstudies for an outreach event, contact MaryLou Gannotti at (860)443-4567.

Do You Pee When You Laugh?

Tuesday, September 15th, 2015

Do you pee when you laugh, cough, sneeze or exercise?  It can be embarrassing and annoying!  Some women tacitly except this condition and chalk it up to once having had big babies or getting older.  Leaking pee when you laugh, cough, sneeze or exercise is called Stress Urinary Incontinence. This is a real medical condition.  Clinical research is currently underway in New London to test a discreet, disposable investigational product that may prevent small bladder leaks that occur when women laugh, cough, sneeze or exercise.

Some women find themselves wearing panty liners or pads 24/7, avoiding activities such as Zumba, and urging people not to make them laugh to avoid urine leaks.  Take a listen to the radio spot below to learn more, or call 860-443-4567.


Welcome Dr. McKnight!

Monday, May 18th, 2015
Melissa Gomez and Craig E. McKnight, MD, PhD

Melissa Gomez and Craig E. McKnight, MD, PhD

CCRstudies welcomes Craig E. McKnight, MD, PhD, and Melissa Gomez, a member of his nursing staff,to our study team.

Dr. McKnight currently serves as the Medical Director at Craig E. McKnight, MD, PhD, LLC, a private gynecology practice in New London located on Montauk Avenue.

Dr. McKnight’s areas of interest include gynecology, urinary incontinence and infertility. He has worked as an OB-GYN in private practice, has been involved in research, and has served as a member of the teaching faculty at Yale New Haven Hospital. Dr. McKnight holds a BS in Zoology from Iowa State University, an MA in Zoology from the University of South Florida, a PhD from the University of Pennsylvania and an MD from Jefferson Medical College.  Dr. McKnight will be working as a Sub-Investigator on some of the clinical research trials at CCRstudies, including the Birth Control study, Decreased Sexual Desire in Women, and Overactive Bladder.

Melissa Gomez, a member of the nursing staff at Craig E. McKnight, MD, PhD, LLC in New London, will be working as a Research Assistant on a variety of trials at CCRstudies. With a focus and training in nursing,  Melissa worked as a Certified Nurse’s Aide for many years, and is a graduate of Norwich Free Academy. Melissa earned a diploma in nursing from Stone Academy in East Hartford and has been trained as an LPN.  Melissa has been working in the medical field for the past several years, and has experience in residential care. Her friendly demeanor and attention to detail will serve her well in the role she plays in the clinical trial process.

We are delighted to welcome Dr. McKnight and Ms. Gomez to the professional team at CCRstudies!

Nightingale Awards

Tuesday, May 5th, 2015


Congratulations to Merrilyn McNatt, APRN.  She will be presented with a Nightingale Award for Excellence in Nursing on Thursday, May 7th, 2015 at the Mashantucket Pequot Museum and Research Center.  She is among 50 nurses who will be recognized for excellence in their profession by the VNA of Southeastern Connecticut, who organize the event.

Merrilyn has worked as a Sub Investigator on a variety of clinical trials at CCRstudies. Ms. McNatt has a BSN from the Medical College of Georgia, a Master’s degree in Maternal/Child  Nursing from the University of Connecticut with  post-graduate work completed at the University of Rhode Island in the area of family practice.

Best wishes to Merrilyn on being recognized for her outstanding contributions to the nursing profession!



Overactive Bladder Study Coming in July

Thursday, June 26th, 2014

If you feel like your frequent and sudden urges to urinate are not the norm, you may be suffering from an overactive bladder.

According to the Mayo Clinic, you may have an overactive bladder if you:

  • Feel a sudden urge to urinate that’s difficult to control
  • Experience urge incontinence — the involuntary loss of urine immediately following an urgent need to urinate
  • Urinate frequently, usually eight or more times in 24 hours
  • Awaken two or more times in the night to urinate (nocturia)

CCRStudies in New London has just been awarded an overactive bladder clinical trial that will begin in July of 2014, led by Dr. Robert Spitz. Further information on the study will be posted on the CCRStudies website at Those who might be eligible to participate in the clinical trial can call CCRStudies at 860-443-4567.